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What causes PIP (Post Injection Pain)

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What causes PIP (Post Injection Pain)
What causes PIP (Post Injection Pain)

What causes PIP (Post Injection Pain)?

What causes (non-infection related) injection pain?

1st – The shorter ester, the higher melting point

2nd – The concentration of the gear

3rd – The solvents used

4th – Injecting too quickly

5th – Virgin muscle

6th – Carbolic Acid (Poor Quality Raw Powders) (Enanthate)



Pain is caused when oil/solvents are absorbed by the body and crystals are left behind.

Short esters (propionate or acetate) are harder, more painful crystals with melting points in the 100c range.

A hormone with longer esters (excluding cypionate – cyp is long but also high melting point) can have a melting point in the 20c – 40c range. Not far off from the human body temp.

Pain is also caused by the concentration of gear

Building off of 1: Let’s say it takes the body 24 hours to absorb 1mL of a certain oil/solvent blend, and 24 hours to absorb 50mg of Testosterone Propionate. If 50mg (or less) of testosterone propionate is in 1mL of that oil, this injection should be painless. On the other hand, if 100mg of testosterone propionate is in that same 1mL of solution, then after 24 hours the body will have absorbed 50mg and 1mL, leaving 50mg behind in the injection area, crystallized and painful.

It is better to shoot 3mL of 50mg/mL Testosterone Propionate than 1mL of 150mg/ML Testosterone Propionate.

This is why water-based suspensions (Testosterone base/no ester, Winstrol) hurt the most, water is very easily absorbed in the body.


The solvents used can cause pain in two ways:

Benzyl alcohol (BA) is used at 1% – 2% as a preservative and antiseptic. If the alcohol content is too high the gear will burn. Pain in the first 24 hours is usually caused by the heavy solvent, pain in the next few hours is caused by crystallization.

Another way is a bad recipe:

If someone used 2% BA, and the rest of the solution oil, the mg/mL would have to be low due to oil’s weak ability to hold crystals. On the other hand, a recipe like 2% BA, 5% Guaiacol (super solvent), 10% Benzyl Salicylate (liquid aspirin) with the filler split 50:50 between Ethyl Oleate (oil/solvent hybrid) and normal oil should be far less painful. Also, Poor Quality Raws can be a cause of PIP.

Pain is also caused if you inject too quickly, it can tear tissue.

If your muscle is new to the hormone, it will absorb the hormone very slowly, but absorb the oil/solvent very quickly. This will cause more crystallization and pain. As your muscle recognizes the hormones, they will be absorbed more quickly thus less pain. The deeper you inject into the center of a muscle group, the better.

How to prevent pain before I inject?

This is the best way. Cut your shots into 50:50 with sterile filtered oil. If you want to use 50mg of Testosterone Propionate, and you have 100mg/mL Testosterone Propionate pull 0.5mL of your test prop, and 0.5mL of sterile filtered oil to shoot 1mL of 50mg/mL Testosterone Propionate. Don’t bother with B-12 it is water based – absorbed so quickly it will have little to no impact.

Before you shoot, it can help to warm your gear some (especially suspensions). You could put the vial in the bathroom sink and let the hot water run over the vial for 2 minutes, and shake well. This will lower the oil's viscosity also making it easier to pull into the syringe.

Inject slowly, take 30 seconds per mL. Use a 25g pin to inject so it forces you to move slowly.

If none of these work you could have dirty gear. It is possible there could be particles (although bacteriostatic) in the gear that is not causing infection but still causes the site infection that made it through a filter.

How do I deal with the pain once I have it?

The worst thing you can do is ice it. The cold will help the crystals fall out of the solution/suspension. It is okay to take some ibuprofen to decrease the swelling and help with the pain.

Pub Time : 2019-01-14 14:18:03 >> News list
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